June 16, 2021
Family Research Council has published a new resource outlining the ethical considerations of human-animal chimera research. In this report, Mary Szoch explains that these lab-developed interspecies creatures are composed of both human and animal DNA.
The report highlights that though the National Institutes of Health (NIH) currently bans federal funding for this area of experimentation, mounting pressure from the International Society for Stem Cell Research (ISSCR) and the apathy of the Biden administration pose risks to the ethical future of federally funded research. A recent amendment introduced by Senator Mike Braun (R-Ind.) that would have banned the creation of human-animal chimeras failed to pass the Senate in a 49-48 party line vote, demonstrating the political division surrounding this issue.
Human-Animal Chimeras: Unethical and Unnecessary delves into the research that has continually blurred ethical lines in the pursuit of “successful” trials and the progression of chimera experimentation. It describes the creation of the 14-Day Rule in 1979, which limits the sustaining of human embryos in vitro to 14 days after fertilization.
When researchers succeeded in sustaining an embryo past nine days in 2016, however, this rule was revisited by the NIH to consider extending researchers the freedom to continue their trials past 14 days. Mary Szoch writes that, “the 14-Day Rule was simply an arbitrary marker allowing scientists to advance to the point science allowed while simultaneously professing that there were ethical limits to the research.” The NIH is once again reconsidering the rule after a scientist partnering with China succeeded in sustaining a human-monkey chimera embryo to 20 days.
The report also considers the purported purpose of human-animal chimera research that occurs despite lack of current federal funding. There is nothing useful to glean from using interspecies chimeras to study human diseases since the research will not consider the factors unique to actual human beings, such as genetic makeup, environment, and diet.
Perhaps most significantly, the report lists major ethical concerns posed by the development of a creature that is part human and part animal: “Is this new creature classified as a human, animal, or both? Will this creature be self-aware? […] Is it ethical to create an organism that has some human characteristics only for the purpose of studying it and using its parts?”
A key conclusion that this report draws from the capricious ethical standards for experimentation with human embryonic cells is that researchers must weigh whether they “should” do something just because they “can” do something.
Christians evaluating the progression of human-chimera research ought to consider 1 Corinthians 6:12, which states, “’All things are lawful for me,’ but not all things are helpful. ‘All things are lawful for me,’ but I will not be dominated by anything.” As believers inhabit a fallen world, they must carefully consider the morality of every decision and advocate for justice when institutions permit evil—especially an evil that denies the dignity of the human person.